Advanced kidney cancer means the disease has spread from its original site in the kidney to other parts of the body. Symptoms may include fatigue, pain, or unexpected weight loss. Management focuses on slowing disease progression with treatments like targeted therapy or immunotherapy, and prioritizing your overall well-being.

Kidney cancer, advanced

Axitinib / Inlyta

Bevacizumab / Avastin

Cabozantinib / Cabometyx

Erlotinib / Tarceva

Everolimus / Affinitor

Levatinib / Lenvima

Pazopanib / Votrient

Sorafenib / Nexavar

Sunitinib / Sutent

Temsirolimus / Torisel 

Immunotherapy for kidney cancer (EAU)

Advanced kidney cancer (EAU)

Patient guide, Kidney Cancer (NCCN)

Novant webpage

Urology Specialists of the Carolinas profile

Cancer is a disease where the body's cells grow abnormally and uncontrollably. Symptoms vary widely depending on the type and location, but common treatments include surgery, chemotherapy, and radiation. While causes are complex, healthy lifestyle choices like diet and exercise can influence risk and overall health.

Cancer basics

Seeing blood in your urine (hematuria) requires medical attention. While often due to infections or kidney stones, it needs investigation to rule out other potential causes. A cystoscopy is a common procedure where a thin, flexible camera is gently inserted to look inside your bladder and urethra, helping your doctor find the source of the bleeding and determine the best next steps. Always discuss any blood in your urine with your healthcare provider promptly.

Blood in the urine & cystoscopy

Bladder cancer occurs when abnormal cells form in your bladder's lining. The most common symptom is blood in urine, sometimes with frequent or painful urination. Smoking is a key cause, along with certain chemical exposures. Treatment options often include surgery, chemotherapy, or immunotherapy, depending on the cancer stage. Adopting a healthy lifestyle, especially quitting smoking, is important for prevention and management.

Bladder cancer

Localized kidney cancer means abnormal cells are found only within the kidney. Often found early, symptoms might include blood in urine or back pain, with causes linked to smoking or obesity. Treatment frequently involves surgery, emphasizing the importance of a healthy lifestyle for overall well-being.

Kidney cancer, localized

Upper tract urothelial carcinoma is cancer that develops in the lining of the kidney or ureter (the tube connecting the kidney to the bladder). Key symptoms often include blood in the urine. While smoking and certain chemical exposures are common risk factors, treatment typically involves surgery, and lifestyle changes like quitting smoking are crucial.

Urothelial Carcinoma of the Upper Tract

An elevated PSA (Prostate-Specific Antigen) blood test can indicate prostate changes, sometimes requiring a prostate biopsy to check for conditions like inflammation, enlargement, or cancer. The biopsy helps your doctor determine the cause and discuss appropriate next steps, which may include monitoring or treatment plans. Maintaining a healthy lifestyle supports overall prostate health.

Elevated PSA and prostate biopsy

Prostate cancer is a common cancer in men, affecting the walnut-sized prostate gland. Early stages often have no symptoms, though risk increases with age and family history. Treatment options vary, from active surveillance to surgery or radiation. Maintaining a healthy lifestyle can be beneficial.

Prostate Cancer

Penile cancer is a rare cancer affecting the skin or tissues of the penis. Symptoms can include skin changes, lumps, unhealing sores, or unusual discharge. Risk factors include HPV and certain lifestyle factors; maintaining good hygiene can help. Treatment often involves surgery or radiation, and early detection is key for better outcomes.

Penile cancer

Testicular cancer is a treatable cancer that begins in the testicles, often appearing as a painless lump, swelling, or heaviness in the scrotum. While its exact causes are unclear (an undescended testicle is a known risk factor), it's highly curable, especially when caught early. Treatment typically involves surgery, sometimes with chemotherapy or radiation, making self-awareness and regular self-exams important for timely detection.

Testicular cancer

A urethral stricture is a narrowing of the urethra, the tube that carries urine out of the body. This can cause symptoms like a weak urine stream, difficulty emptying your bladder, or pain. It often results from injury, inflammation, or infection. Thankfully, it's a treatable condition to restore normal urine flow.

Urethral stricture

UPJ Obstruction is a blockage where your kidney connects to the ureter, the tube that carries urine to the bladder. This can cause urine to back up, leading to symptoms like side pain, nausea, or infection. It can be present from birth or develop later, and treatments are available to ensure proper kidney drainage and health.

UPJ obstruction

Low testosterone (low T) occurs when your body doesn't produce enough of this key male hormone. Symptoms often include fatigue, reduced sex drive, mood changes, and decreased muscle/bone mass. Causes range from aging and health conditions to lifestyle factors; management may involve lifestyle adjustments (like diet and exercise) and, if appropriate, hormone therapy, all discussed with your doctor.

Low testosterone

Kidney stones are hard deposits that form in your kidneys, often causing severe back or side pain and sometimes blood in the urine. They can be linked to dehydration or diet. While painful, many pass with increased fluids, or medical procedures may be needed for larger stones. Staying well-hydrated is crucial for prevention.

Kidney stones

Kidney cysts are common, fluid-filled sacs that can form in the kidneys. Many are harmless, cause no symptoms, and require no treatment. Others may need monitoring or intervention if they grow large, cause pain, or affect kidney function. Maintaining a healthy lifestyle generally supports kidney health.

Kidney cysts

Male incontinence is the unintentional leakage of urine, often due to weakened bladder muscles, prostate issues, or nerve damage. It's a common and treatable condition, manageable through lifestyle changes, exercises, medication, or other medical interventions. Discussing symptoms with a healthcare provider can help find effective solutions to improve quality of life.

Incontinence, male

Benign Prostatic Hyperplasia (BPH), or enlarged prostate, is a very common, non-cancerous condition where the prostate gland grows with age. This growth can press on the urethra, causing urinary symptoms like frequent urges, a weak stream, or waking up at night to urinate. It's often managed through lifestyle adjustments, medications, or, in some cases, minor procedures to help you feel more comfortable.

BPH, Enlarged Prostate

Erectile dysfunction (ED) is when a man has difficulty getting or keeping an erection firm enough for sexual activity. This common condition can be caused by physical factors like diabetes or heart disease, psychological stress, or lifestyle choices. Effective treatments and lifestyle changes, such as healthy diet and exercise, can often help improve ED.

Erectile dysfunction

Kyle Johnson

Urologic Oncologic Surgeon

Surgery (Urology)

Cancer conditions affecting the bladder, the organ storing urine.

Conditions affecting your bladder, kidneys, and how you urinate.

Bladder and Urinary Issues

Diseases where body cells grow abnormally and can spread.

Cancer

Conditions where your body bleeds too easily or can't stop bleeding.

Bleeding Concerns

Problems that stop urine from flowing freely from your kidneys, bladder, or tubes.

Blockages in the Urinary Tract

Prostate problems that affect men's urination and health.

Prostate Conditions

Everyday health, wellness tips, and understanding how to manage your care.

General Health & Patient Education

Kidney Cancer

Cancers that start in the prostate gland, a male reproductive organ.

Problems with bladder, bowel, pain, or pelvic organ support.

Pelvic Floor & Pelvic Health

Conditions causing accidental urine leakage or loss of bladder control.

Urinary Incontinence

Conditions affecting your kidneys and the tubes that carry urine.

Kidney & Ureter Conditions

Conditions from hard, stone-like deposits in kidneys and urinary tract.

Kidney Stones

Conditions affecting male organs, fertility, and sexual health.

Men's Reproductive Health

Tests to find what's wrong or to check for health problems.

Screening and Diagnostic Procedures

Health conditions affecting sex organs, fertility, & sexual well-being.

Kyle Johnson, MD

Kidney cancer, advanced

Recommended Resources

Common Medication for Kidney cancer, advanced

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